Bedlington Terrier
Bedlington Terriers have a cited life expectancy of 13.7 years (McMillan 2024 / VetCompass, n=1,294, 95% CI 13.4 to 14). Only 11 Bedlington Terriers have been tested for disease variants (Donner 2023), too few to say which variants the breed has. Only 11 dogs stand behind the atlas figures here, so little is known yet.
Also known as Rodbery Terrier, Rothbury Terrier, and Rothbury's Lamb.
Which disease variants turn up in Bedlington Terriers?
From a panel of 250 Mendelian-disease variants screened in 1,054,293 dogs (Donner et al. 2023), 6 turn up in Bedlington Terriers at observable frequency. The figure beside each is its allele frequency. Of the gene copies tested in this breed, the share that carry the variant. Every dog carries two copies, so this is not the share of dogs. It is not clinical risk. Most recessive variants require two copies for disease expression; many dominant variants show incomplete penetrance. Read this as a population fingerprint of what's in the gene pool, not a per-dog prediction.
FGF4what this gene does
FGF4 influences leg length by affecting bone growth, leading to shorter legs in certain breeds.
For your dog: If your dog is from a breed known to carry this gene, it's worth discussing spinal health with your vet, but being a carrier doesn’t guarantee problems.
SLC7A9what this gene does
SLC7A9 is a gene that helps transport certain amino acids in the kidneys. It plays a role in how the body handles cystine, an amino acid that can form crystals.
For your dog: If your dog is a carrier, it’s worth discussing with your vet to monitor urinary health and catch any issues early.
RPGRIP1what this gene does
RPGRIP1 is a gene involved in the function of photoreceptor cells in the eye, which help dogs see in different light conditions.
For your dog: If your dog belongs to a breed known to carry RPGRIP1 mutations, it’s worth discussing with your vet to understand the risks and monitor eye health.
PDK4what this gene does
PDK4 helps regulate how cells use energy, especially in the heart muscle.
For your dog: If your dog is one of the breeds known to carry this gene, it’s worth discussing heart health with your vet, but being a carrier doesn’t mean your dog will develop disease.
ENAMwhat this gene does
ENAM is a gene that helps form enamel, the hard outer layer of teeth. It plays a key role in making sure teeth develop strong and smooth.
For your dog: If your dog is from one of these breeds, it’s worth asking your vet about ENAM and dental health, especially if you notice unusual wear or discoloration on their teeth.
What these results mean for a Bedlington Terrier
About 23 in every 100 copies of this gene in the 11 Bedlington Terriers tested carry this change (Donner 2023).
- Extra copies of a growth gene called FGF4 shape a dog's legs and back. The copy on chromosome 12 is the one linked to disc disease. The copy on chromosome 18 makes legs shorter.
OMIA 000157-9615
“Two FGF4 retrogenes (FGF4L1 on chromosome 18 and FGF4L2 on chromosome 12) have been identified to cause dwarfism across many dog breeds.” OMIA 000157-9615
“Brown et al. (2017) reported that an FGF4 retrogene insertion in chromosome CFA12” OMIA 000157-9615
- Carrying it raises the risk, but it can't tell you which dog will have a disc problem. In Dachshunds, researchers found the test on its own isn't a reliable guide.
OMIA 000157-9615
“the FGF4 retrogene insertion on CFA12 is not a valid risk indicator on its own” OMIA 000157-9615
What to do
Ask your vet what the result means for your dog. The sources here don't say what lowers the risk for a dog that carries it.
Not tested, or a mix
Without a test, no one can tell. Short legs don't tell you either: the disc copy and the short-leg copy are different.
A bladder-stone (cystinuria) test that doesn't hold up
Not a reliable testAbout 41 in every 100 copies of this gene in the 11 Bedlington Terriers tested carry this change (Donner 2023).
- Some DNA tests check this gene change for bladder stones. The researchers who studied it found it doesn't cause them, and they advise against using it as a test.
OMIA 001880-9615
“there appears to be no support for the variant to be causal” OMIA 001880-9615
“strongly recommend not to use "the variant in SLC7A9 as a test to predict the risk of developing cystinuria in male English bulldogs.” OMIA 001880-9615
What to do
A result for this change, either way, tells you nothing about bladder stones. If your dog strains to pee or there's blood in the urine, see a vet, whatever a DNA test said.
Not tested, or a mix
Nothing to do. There's no reason to test for this one.
A heart (DCM) test that doesn't hold up
Not a reliable testAbout 5 in every 100 copies of this gene in the 11 Bedlington Terriers tested carry this change (Donner 2023).
- This gene change was linked to a heart disease called DCM in Dobermans, but it hasn't been shown to cause it. The curated record says a test for it isn't a good guide to heart risk, even in Dobermans.
OMIA 000162-9615
“it is evident that any DNA test based on this marker will not be a good indicator of liability to this disorder in Dobermans” OMIA 000162-9615
What to do
A result for this one isn't, by itself, a reason for heart tests. Whether to check your dog's heart is a conversation to have with your vet.
Not tested, or a mix
Outside the Doberman, no one has shown what this change means.
Other names
The Bedlington Terrier is also recorded as Rodbery Terrier, Rothbury Terrier, and Rothbury's Lamb.
Identified as Bedlington Terrier (VBO:0200137) in the Vertebrate Breed Ontology (Mullen et al. 2025, CC-BY 4.0) · registry IDs FCI 9 · iDog 27 · VeNom 14957.
For researchers Population genetics, disease models and every recorded condition Open the research detail for the Bedlington Terrier
In the atlas, the Bedlington Terrier clusters consistently as Bedlington Terrier (100% of the 11 dogs here). Dogs here sit in a relatively sparse region of the atlas, fewer close neighbors than typical.
Only 11 dogs of this breed in the atlas, modestly sampled.
What the atlas genotypes say about Bedlington Terrier
Computed from the 14,478 CanVAS dogs in the Atlas, on an imputed genotype backbone: 77,215 directly typed sites per dog, imputed to 9.67 million variants.
The confidence below counts dogs, not reads: it is the size of the sample, and it is separate from how the genotypes were measured.
Not enough dogs in the atlas yet (n=11) for a reliable diversity figure. It fills in as more are added.
What does genetic diversity mean?
How varied a breed's gene pool is — the share of gene spots where a typical dog of the breed carries two different versions rather than two identical ones.
How to read it: Higher = more diverse. Among well-sampled breeds it ranges roughly 0.22 (least diverse) to 0.33 (most diverse).
Diversity is a strength, not a verdict on any individual dog. Lower diversity means it's worth paying attention to recessive-risk testing — not that a dog is doomed.
Not enough dogs in the atlas yet (n=11) to resolve cluster structure. It fills in as more are added.
What does within-breed variation mean?
How much individual dogs within the breed differ from each other genetically.
How to read it: Higher = more internal variety among individuals of the breed.
Sensitive to how many dogs of the breed we've sampled.
What does typical lifespan mean?
The median age dogs of the breed tend to reach.
How to read it: Higher = longer-lived. Compare to longevity-for-size to see whether it's just a size effect.
Drawn from population lifespan records; individual dogs vary widely with care, genetics, and luck.
Bedlington Terriers are a natural model for human disease
Because the same genes cause the same conditions across species, the inherited conditions documented in Bedlington Terriers help researchers understand, and work toward treating, the human diseases they model. This is the dog advancing human medicine. The breed models the human disease; it does not have it, and this is not a prediction for your dog.
- OMIM:607238, modeled by the breed's Copper toxicosis, COMMD1-related via COMMD1, the same underlying biology.
- OMIM:615886, modeled by the breed's Hyperkeratosis, palmoplantar, FAM83G-related , the same underlying biology.
- Wilson disease, modeled by the breed's Wilson disease , the same underlying biology.
Every condition recorded in the Bedlington Terrier
Beyond the testable carriers above, OMIA's literature catalogue records 3 genetic conditions in the Bedlington Terrier, 3 of which have a known human equivalent. This is the documented landscape across all Bedlington Terriers ever studied, not a prediction for any one dog.
- Copper toxicosis, COMMD1-related Autosomal recessiveHuman equivalent: OMIM:607238
- Hyperkeratosis, palmoplantar, FAM83G-related Autosomal recessiveHuman equivalent: OMIM:615886
- Wilson disease Autosomal recessiveHuman equivalent: Wilson disease
Where every number on this page came from.
This page draws on three primary data sources. Allele frequencies for the Mendelian section come from Donner et al. 2023 (CC-BY-4.0). We grade these data at evidence Limited because the cohort is a direct-to-consumer ascertainment, which biases toward owners who chose to test their dogs. The panel also uses tag-SNP proxies for some variants rather than direct causal-variant assays. Limited is a study-design grade, not a quality grade: the Donner cohort is the largest open canine-genotype dataset in existence and we are grateful for it. We rate the confounding MEDIUM.
Population-genetic dimensions (heterozygosity, intra-breed PCA distance, nearest neighbors, trait-locus frequencies) come from CanVAS (Brundage 2026), harmonized through the Sniff Atlas. The exact release date and verification commit are pinned at the bottom of the page so a researcher can trace a number back to a specific snapshot. The disease-gene-variant graph comes from OMIA (Online Mendelian Inheritance in Animals; Nicholas, Tammen, and the Sydney Informatics Hub at the Sydney School of Veterinary Science, The University of Sydney; retrieved April 2026, DOI 10.25910/2AMR-PV70).
What this page does not yet have. Inheritance modes and per-disease penetrance evidence from Donner 2023 are in the structured data for every variant the panel covers. Mondo, OMIM, Ensembl, and HGNC cross-references live on the gene and disease pages this page links to, rather than being repeated here. What is still absent from this breed page is anything not in the cited panel, and each such gap carries its cause where it appears.
How to cite this page. The computed dimensions on this page are derived from the open Sniff Atlas v1.0.2 (Gehring 2026, doi:10.5281/zenodo.20566358, CC-BY 4.0). Full citation formats including BibTeX, RIS, and CITATION.cff at sniff.world/cite.
Some things about living with a bedlington terrier never make it into a database. Add what you know as a Keeper, in your words →
Lived experience, kept beside the science.We have 11 bedlington terriers. We do not have yours.
Every bedlington terrier added sharpens the breed's genetic neighborhood. Enrollment is free. The data stays open. The star is permanent.
- Donner J, Freyer J, Davison S, Anderson H, Blades M, Honkanen L, et al. (2023). Genetic prevalence and clinical relevance of canine Mendelian disease variants in over one million dogs. PLOS Genetics 19(2):e1010651. doi:10.1371/journal.pgen.1010651
- Brundage DM (2026). CanVAS: A Harmonized and Imputed Canine Variant Atlas. bioRxiv. doi:10.64898/2026.04.13.718238
- Nicholas, F.W., Tammen, I., & Sydney Informatics Hub. (2026). Online Mendelian Inheritance in Animals (OMIA) [dataset]. The University of Sydney. https://omia.org. doi:10.25910/2AMR-PV70 (retrieved April 2026).