FGF4_retrogene_CFA18
chondrodysplasia insertion site; not annotated as gene
The famous FGF4 retrogene insertion on chromosome 18 (Parker 2009).
breed is standard-legged - does NOT carry the chondrodystrophy retrogene insertion (the alt allele at this rep SNP marks the non-retrogene haplotype)
breed carries the FGF4 chr18 retrogene insertion (Parker 2009) - causal for short legs in Dachshund/Corgi/Basset Hound. Spot-check confirms: Dachshund, Pembroke Corgi, Pekingese, Basset variants all read ~0 at this rep SNP.
Where the leg length variant sits across every breed with data, by allele frequencyAllele frequencyWhat it isHow common a gene variant is across dogs, from 0% (none carry it) to 100% (all do).For your dogA high number means it's common in the breed. It does not tell you whether your own dog carries it.PreciselyThe proportion of sampled chromosomes in a population that carry the variant allele.Sniff Atlas (CanVAS) · measured · Ask about this → and grouped by AKC breed groupAKC breed groupWhat it isThe American Kennel Club's grouping of breeds by the job they were bred for: Sporting, Hound, Working, Herding, Terrier, Toy, Non-Sporting.PreciselyAKC parent-group classification. A registry convention reflecting historical use, not a genetic grouping.American Kennel Club · registry convention. Each tick is one breed; a variant fixed in one group and absent in another shows up as a gap. These come from one marker per trait, so read them as a tag, not a verdictA trait tag, not a verdictWhat it isThese frequencies come from one marker per trait. It predicts the trait for most breeds, but there are real exceptions.For your dogRead it as a tendency for the breed, never as a guarantee about your dog. One marker is not the whole story.PreciselySingle-SNP trait proxies are population tags, not deterministic genotype-to-phenotype calls. Penetrance, modifier loci, and breed-specific haplotypes cause exceptions (for example, the MSRB3 ear-type tag misreads Toy Poodles and Belgian Sheepdogs).Sniff Atlas methodology · known limitation, stated · Ask about this →: accurate for most breeds, with real exceptions.
- 100% n=286
- 100% n=59
- 100% n=48
- 100% n=41
- 100% n=31
- 100% n=30
- 100% n=25
- 100% n=23
- 100% n=23
- 100% n=20
- 0% n=24
- 0% n=26
- 0% n=32
- 0% n=42
- 1% n=97
- 1% n=38
- 2% n=96
- 2% n=54
- 3% n=34
- 6% n=26
108 breeds with fewer than 20 genotyped dogs are not ranked here. At that sample size a single dog swings the frequency, so the figure is not yet stable enough to compare.
Frequency is measured at the typed-backbone 18:20697946 on chr18, 20.7 Mb (inside the gene body). Alleles T/C. Coordinates from manual position (Ensembl symbol failed). Per-breed frequencies are computed across all CanVAS dogs labelled with that breed (missing genotypes excluded).
The per-breed allele frequencies on this page are derived from the open Sniff Atlas v1.0.1 (Gehring 2026, doi:10.5281/zenodo.20566358, CC-BY 4.0). The underlying genotype substrate is CanVAS (Brundage 2026, doi:10.64898/2026.04.13.718238), and disease associations are grounded in OMIA. Full citation formats including BibTeX, RIS, and CITATION.cff at sniff.world/cite.