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Body Size

LCORL

chr3:91,736,902-91,890,160 ·

NCAPG/LCORL height locus chr3

Atlas-wide
83%
dog-weighted average
Breeds with data
215
of 215
Dogs contributing
13,914
CanVAS Atlas
What the frequency means

LCORL/NCAPG chr3:91.7Mb. The body-size locus shared with horses, cattle, and humans. Direction: SMALL vs GIANT.

High frequency means

allele common in giant breeds

Low frequency means

allele common in small breeds

Frequency landscape

Where the body size variant sits across every breed with data, by and grouped by . Each tick is one breed; a variant fixed in one group and absent in another shows up as a gap. These come from one marker per trait, so read them as a : accurate for most breeds, with real exceptions.

0%50%100%
mixed_unknown3 breeds · mean 96%
toy18 breeds · mean 93%
terrier22 breeds · mean 91%
non_sporting22 breeds · mean 87%
sporting19 breeds · mean 84%
hound20 breeds · mean 82%
other16 breeds · mean 80%
herding17 breeds · mean 78%
ancient_landrace57 breeds · mean 77%
working21 breeds · mean 51%
n = 13,914 dogs · CanVAS Atlas (Brundage et al. 2026) · Sniff Atlas
Allele frequency across 215 breeds with data, grouped by AKC breed group. Each accent tick is one breed (fainter = fewer dogs sampled); the bone marker is the group mean. Frequencies are population-level.
Top 10 breeds, highest frequency
  1. Cairn Terrier terrier
    100% n=120
  2. 100% n=102
  3. Maltese toy
    100% n=96
  4. 100% n=67
  5. Border Terrier terrier
    100% n=59
  6. Dingo Captive ancient_landrace
    100% n=59
  7. Havanese toy
    100% n=54
  8. 100% n=52
  9. 100% n=49
  10. 100% n=48
Bottom 10 breeds, lowest frequency
  1. Great Dane working
    0% n=30
  2. Irish Wolfhound ancient_landrace
    0% n=286
  3. 5% n=20
  4. 6% n=117
  5. Akita working
    7% n=22
  6. Basset Hound hound
    13% n=34
  7. German Shepherd herding
    15% n=381
  8. Giant Schnauzer terrier
    18% n=126
  9. Poodle non_sporting
    36% n=55
  10. Mastiff working
    38% n=32

108 breeds with fewer than 20 genotyped dogs are not ranked here. At that sample size a single dog swings the frequency, so the figure is not yet stable enough to compare.

Methodology

Frequency is measured at the typed-backbone 3:91717919 on chr3, 91.7 Mb (19 kb from the gene body). Alleles A/G. Coordinates from ensembl symbol UU Cfam GSD 1.0. Per-breed frequencies are computed across all CanVAS dogs labelled with that breed (missing genotypes excluded).

In the reference databases

LCORL as it is catalogued across the genomics world. Each link is the canonical record, so this gene composes with everything those resources know.

The human counterpart

In humans, this gene's counterpart is LCORL. That ortholog is what connects LCORL to a century of human medical genetics. The dog and human proteins are 82% identical.

In people, LCORL rarely tolerates loss-of-function variation (gnomAD v4.1 constraint, LOEUF 0.34), a sign it does important, dosage-sensitive work.

How to cite this page

The per-breed allele frequencies on this page are derived from the open Sniff Atlas v1.0.1 (Gehring 2026, doi:10.5281/zenodo.20566358, CC-BY 4.0). The underlying genotype substrate is CanVAS (Brundage 2026, doi:10.64898/2026.04.13.718238), and disease associations are grounded in OMIA. Full citation formats including BibTeX, RIS, and CITATION.cff at sniff.world/cite.

Last updated
Sources: Sniff Atlas v1.0.1 (doi:10.5281/zenodo.20566358) · CanVAS (Brundage 2026) · OMIA · Dog10K (Meadows 2023) · gnomAD v4.1 (Karczewski 2020)